Free HESI A2 Anatomy and Physiology guide

November 2026 - Anatomical Terminology Study Guide

Anatomical terminology gives every body relationship a fixed reference point. Directional terms, planes and regions are interpreted from anatomical position, so they remain precise regardless of how a patient or diagram is turned.

Updated November 2026

Anatomy and Physiology guide Foundations 4 min read

Practice As You Read

Try 3 short questions throughout this guide. Check each answer to learn from the explanation.

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Core ideas to know

Learn the relationships, not a string of isolated definitions. These are the facts that let you reason through unfamiliar wording.

  • Anatomical position is standing upright, facing forward, arms at the sides and palms facing forward.
  • Superior/inferior compare vertical position; anterior/posterior compare front and back.
  • Medial/lateral compare distance from the midline; proximal/distal compare distance from a limb’s attachment.
  • A sagittal plane divides left and right, a frontal plane anterior and posterior, and a transverse plane superior and inferior.
  • Superficial/deep compare distance from the body surface; the terms do not describe severity.
Bodies intersected by sagittal, frontal and transverse planes beside a profile showing the major dorsal and ventral body cavities.
Name a plane from the portions it creates, not the angle at which it is drawn: left/right, front/back or upper/lower.

A reliable way to answer

Use the same short process every time so the wording of the question does not decide your method for you.

  1. Mentally place the body in anatomical position before reading the relationship.
  2. Identify whether the structures are compared along a vertical, front–back, midline, limb or depth axis.
  3. Choose the matching pair of opposites and state the relationship in both directions.
  4. For planes, name the portions produced rather than relying on the drawing’s orientation.

Question 1 of 3

In anatomical position, the thumb is _____ to the little finger.

Answer Choices for Question 1

View the Answer and Explanation

Correct answer: B. lateral

With palms facing forward, the thumb lies farther from the body’s midline than the little finger and is therefore lateral to it.

Distinctions that earn marks

IdeaWhat it meansDo not confuse it with
Medial Closer to the midline Lateral, farther from the midline
Proximal Closer to a limb’s attachment Distal, farther from its attachment
Sagittal plane Divides left and right Frontal plane, divides front and back

Read every word in the stem before choosing. HESI distractors are often true statements that answer a nearby question rather than the one that was asked.

Terms to know

Ipsilateral
On the same side of the body.
Contralateral
On opposite sides of the body.
Midsagittal
A plane dividing the body into equal left and right halves.

Question 2 of 3

The elbow is _____ to the wrist.

Answer Choices for Question 2

View the Answer and Explanation

Correct answer: C. proximal

The elbow lies closer than the wrist to the upper limb’s attachment at the shoulder, making the elbow proximal to the wrist.

Key points

  • All directional terms assume anatomical position.
  • Proximal and distal are most useful along limbs or branching structures.
  • Name a plane from the body portions it creates, not the angle of the page.

Question 3 of 3

Which plane divides the body into anterior and posterior portions?

Answer Choices for Question 3

View the Answer and Explanation

Correct answer: C. Frontal

A frontal, or coronal, plane separates front from back. Sagittal separates left and right, while transverse separates superior and inferior portions.

HESI · Anatomical terminology

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